Dear Maintainer,

   * What led up to the situation?

using embedded perl (like recommended) for mimedefang-multiplexor

   * What exactly did you do (or not do) that was effective (or
     ineffective)?

md-mx-ctrl reread

   * What was the outcome of this action?

"Cannot destroy and recreate an embedded Perl interpreter safely on this platform.  Filter rules will NOT be reread"

   * What outcome did you expect instead?

mimedefang-multiplexor to be reloaded.

This is the same error as in
https://bugs.debian.org/cgi-bin/bugreport.cgi?bug=516913
which was solved via
https://sources.debian.org/patches/mimedefang/2.84-4/embperl.patch/
which is still included.